DNA polymerase I is not required for replication of linear chromosomes in streptomyces.
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ABSTRACT:
SUBMITTER: Huang TW
PROVIDER: S-EPMC2223709 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Publications
DNA polymerase I is not required for replication of linear chromosomes in streptomyces.
Huang Tzu-Wen TW Chen Carton W CW
Journal of bacteriology 20071109 2
Both polA (encoding DNA polymerase I; Pol I) and a paralog were deleted from Streptomyces strains. Despite the UV sensitivity and slow growth caused by the DeltapolA mutation, the double mutant was viable. Thus, in contrast to a previous postulate, Pol I and its paralog are not essential for replication of Streptomyces chromosomes. ...[more]
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