Ontology highlight
ABSTRACT:
SUBMITTER: Neoh HM
PROVIDER: S-EPMC2223914 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Neoh Hui-min HM Cui Longzhu L Yuzawa Harumi H Takeuchi Fumihiko F Matsuo Miki M Hiramatsu Keiichi K
Antimicrobial agents and chemotherapy 20071022 1
Multistep genetic alteration is required for methicillin-resistant Staphylococcus aureus (MRSA) to achieve the level of vancomycin resistance of vancomycin-intermediate S. aureus (VISA). In the progression of vancomycin resistance, strains with heterogeneous vancomycin resistance, designated hetero-VISA, are observed. In studying the whole-genome sequencing of the representative hetero-VISA strain Mu3 and comparing it with that of closely related MRSA strains Mu50 (VISA) and N315 (vancomycin-sus ...[more]