Ontology highlight
ABSTRACT:
SUBMITTER: Lin LC
PROVIDER: S-EPMC5783010 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Lin Lee-Chung LC Chang Shih-Cheng SC Ge Mao-Cheng MC Liu Tsui-Ping TP Lu Jang-Jih JJ
Infection and drug resistance 20180118
Prolonged vancomycin usage may cause methicillin-resistant <i>Staphylococcus aureus</i> to become vancomycin-intermediate <i>S. aureus</i> (VISA) and heterogeneous VISA (hVISA). Mechanisms of vancomycin resistance of VISA and hVISA are still unclear. In this study, analyses of nucleotide sequence variations in 30 vancomycin-sensitive <i>S. aureus</i> (VSSA), 41 hVISA and 16 VISA isolates revealed 29 single-nucleotide variations in 12 genes (<i>fmtC</i>, <i>graR</i>, <i>graS</i>, <i>htrA</i>, <i> ...[more]