Ontology highlight
ABSTRACT:
SUBMITTER: Rodrigues ML
PROVIDER: S-EPMC2224146 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Rodrigues Marcio L ML Nakayasu Ernesto S ES Oliveira Debora L DL Nimrichter Leonardo L Nosanchuk Joshua D JD Almeida Igor C IC Casadevall Arturo A
Eukaryotic cell 20071126 1
Cryptococcus neoformans produces vesicles containing its major virulence factor, the capsular polysaccharide glucuronoxylomannan (GXM). These vesicles cross the cell wall to reach the extracellular space, where the polysaccharide is supposedly used for capsule growth or delivered into host tissues. In the present study, we characterized vesicle morphology and protein composition by a combination of techniques including electron microscopy, proteomics, enzymatic activity, and serological reactivi ...[more]