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Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile.

ABSTRACT: In this study, the tet(W) gene region of a human clinical isolate of Clostridium difficile resistant to tetracycline was characterized. This gene was a new allele showing 99% sequence identity to the gene found in the human strain Bifidobacterium longum F8, and it is not transferable by "in vitro" mating experiments.

SUBMITTER: Spigaglia P

PROVIDER: S-EPMC2224778 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature

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Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile.

Spigaglia Patrizia P Barbanti Fabrizio F Mastrantonio Paola P

Antimicrobial agents and chemotherapy 20071210 2

In this study, the tet(W) gene region of a human clinical isolate of Clostridium difficile resistant to tetracycline was characterized. This gene was a new allele showing 99% sequence identity to the gene found in the human strain Bifidobacterium longum F8, and it is not transferable by "in vitro" mating experiments. ...[more]

PMID: 18070963

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