Ontology highlight
ABSTRACT:
SUBMITTER: Jin L
PROVIDER: S-EPMC22374 | biostudies-literature | 1999 Mar
REPOSITORIES: biostudies-literature
Jin L L Underhill P A PA Doctor V V Davis R W RW Shen P P Cavalli-Sforza L L LL Oefner P J PJ
Proceedings of the National Academy of Sciences of the United States of America 19990301 7
Despite mounting genetic evidence implicating a recent origin of modern humans, the elucidation of early migratory gene-flow episodes remains incomplete. Geographic distribution of haplotypes may show traces of ancestral migrations. However, such evolutionary signatures can be erased easily by recombination and mutational perturbations. A 565-bp chromosome 21 region near the MX1 gene, which contains nine sites frequently polymorphic in human populations, has been found. It is unaffected by recom ...[more]