Ontology highlight
ABSTRACT:
SUBMITTER: Gorman J
PROVIDER: S-EPMC2253248 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Gorman Jason J Shapiro Lawrence L
Protein science : a publication of the Protein Society 20051201 12
The tryptophan repressor binding protein WrbA binds to the tryptophan repressor protein TrpR. Although the biological role of WrbA remains unclear, it has been proposed to function in enhancing the stability of TrpR-DNA complexes. Sequence database analysis has identified WrbA as a founding member of a flavodoxin-like family of proteins. Here we present crystal structures of WrbA from Deinococcus radiodurans and Pseudomonas aeruginosa and their complexes with flavin mononucleotide. The protomer ...[more]