Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez LE
PROVIDER: S-EPMC2253348 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20050701 7
Receptor-ligand interactions between synthetic peptides and normal human erythrocytes were studied to determine Plasmodium falciparum merozoite surface protein-3 (MSP-3) FC27 strain regions that specifically bind to membrane surface receptors on human erythrocytes. Three MSP-3 protein high activity binding peptides (HABPs) were identified; their binding to erythrocytes became saturable, had nanomolar affinity constants, and became sensitive on being treated with neuraminidase and trypsin but wer ...[more]