Ontology highlight
ABSTRACT:
SUBMITTER: Millan JL
PROVIDER: S-EPMC2254479 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Purinergic signalling 20060617 2
Our knowledge of the structure and function of alkaline phosphatases has increased greatly in recent years. The crystal structure of the human placental isozyme has enabled us to probe salient features of the mammalian enzymes that differ from those of the bacterial enzymes. The availability of knockout mice deficient in each of the murine alkaline phosphatase isozymes has also given deep insights into their in vivo role. This has been particularly true for probing the biological role of bone al ...[more]