Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come?
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ABSTRACT:
SUBMITTER: de Lamballerie X
PROVIDER: S-EPMC2266737 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Publications
Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come?
de Lamballerie Xavier X Leroy Eric E Charrel Rémi N RN Ttsetsarkin Konstantin K Higgs Stephen S Gould Ernest A EA
Virology journal 20080227
Since 2004, several million indigenous cases of Chikungunya virus disease occurred in Africa, the Indian Ocean, India, Asia and, recently, Europe. The virus, usually transmitted by Aedes aegypti mosquitoes, has now repeatedly been associated with a new vector, Ae. Albopictus. Analysis of full-length viral sequences reveals three independent events of virus exposure to Ae. Albopictus, each followed by the acquisition of a single adaptive mutation providing selective advantage for transmission by ...[more]
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