Ontology highlight
ABSTRACT:
SUBMITTER: Lewis C
PROVIDER: S-EPMC2266914 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Lewis Caroline C Baro Marta F MF Marques Margarita M Grüner Myriam M Alonso Angel A Bravo Ignacio G IG
Virology journal 20080226
The human papillomavirus type 16 E5 protein (HPV16 E5) is 83 amino acids in length and contains three well-defined hydrophobic regions. The protein is expressed at very limited amounts in transfected cells and the absence of specific antibodies has strongly hampered functional analyses. To investigate the relationship between structure and function we have synthesized a codon-adapted version of the gene (hE5) and prepared a series of N-terminal and C-terminal deletions. Immunofluorescence analys ...[more]