Ontology highlight
ABSTRACT:
SUBMITTER: Harlow LS
PROVIDER: S-EPMC2286726 | biostudies-literature | 2004 Mar
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20040206 3
RNase PH is a member of the family of phosphorolytic 3' --> 5' exoribonucleases that also includes polynucleotide phosphorylase (PNPase). RNase PH is involved in the maturation of tRNA precursors and especially important for removal of nucleotide residues near the CCA acceptor end of the mature tRNAs. Wild-type and triple mutant R68Q-R73Q-R76Q RNase PH from Bacillus subtilis have been crystallized and the structures determined by X-ray diffraction to medium resolution. Wild-type and triple mutan ...[more]