Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Martin E
PROVIDER: S-EPMC2292154 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
García-Martín Elena E Ayuso P P Luengo Antonio A Martínez Carmen C Agúndez José Ag JA
BMC medical genetics 20080317
<h4>Background</h4>Changes in the density and expression of histamine receptors (HRH) have been detected in Parkinson's disease (PD) patients, and HRH antagonists bring about improvements in motor and other symptoms, thus suggesting that HRH play a role in the clinical response of PD patients. This study is aimed to analyse polymorphic variations of HRH in patients with PD.<h4>Methods</h4>Leukocytary DNA from 195 PD patients and a control group of 231 unrelated healthy individuals was studied fo ...[more]