Ontology highlight
ABSTRACT:
SUBMITTER: Oelgeschlager M
PROVIDER: S-EPMC2311381 | biostudies-literature | 2004 Feb
REPOSITORIES: biostudies-literature
Oelgeschläger Michael M Tran Uyen U Grubisic Kristina K De Robertis Edward M EM
The International journal of developmental biology 20040201 1
Twisted Gastrulation (Tsg) is a secreted molecule which regulates BMP signalling in the extracellular space as part of an evolutionarily conserved network of interacting proteins. In Xenopus, maternal xTsg mRNA can be found throughout the early embryo. After gastrulation, xTsg is expressed as part of the BMP4 synexpression group until late tadpole stages. Here we report the identification of a second Xenopus Tsg gene (xTsg-2). Xenopus Tsg-2 is highly homologousto xTsg. In particular, amino acid ...[more]