Ontology highlight
ABSTRACT:
SUBMITTER: Hu CK
PROVIDER: S-EPMC2315668 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
The Journal of cell biology 20080414 2
During cytokinesis, a specialized set of proteins is recruited to the equatorial region between spindle poles by microtubules and actin filaments, enabling furrow assembly and ingression before cell division. We investigate the mechanisms underlying regional specialization of the cytoskeleton in HeLa cells undergoing drug-synchronized monopolar cytokinesis. After forced mitotic exit, the cytoskeleton of monopolar mitotic cells is initially radially symmetric but undergoes a symmetry-breaking rea ...[more]