Ontology highlight
ABSTRACT:
SUBMITTER: Mendez S
PROVIDER: S-EPMC2323443 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Mendez Susana S Hatem Christine L CL Kesavan Anup K AK Lopez-Molina Javier J Pitt M Louise M ML Dannenberg Arthur M AM Manabe Yukari C YC
Veterinary immunology and immunopathology 20071117 1-2
We sought to characterize the lung cellular immune responses to inhaled Mycobacterium tuberculosis (Mtb) of the susceptible inbred Thorbecke rabbit (the genomically sequenced strain, now unavailable) and compare it to outbred, Mtb-resistant, New Zealand White rabbits. Using Mtb CDC1551, we confirmed that the inbred rabbits allowed establishment of infection with this low virulence strain, compared to poor establishment in outbred rabbits. With a more virulent strain, Mtb Erdman, that establishes ...[more]