Ontology highlight
ABSTRACT:
SUBMITTER: Gemel J
PROVIDER: S-EPMC2323682 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Gemel Joanna J Lin Xianming X Collins Raymond R Veenstra Richard D RD Beyer Eric C EC
Biochemical and biophysical research communications 20080220 2
Since most cells in the heart co-express multiple connexins, we studied the possible heteromeric interactions between connexin30.2 and connexin40, connexin43 or connexin45 in transfected cells. Double-label immunofluorescence microscopy showed that connexin30.2 extensively co-localized with each co-expressed connexin at appositional membranes. When Triton X-100 solubilized connexons were affinity purified from co-expressing cells, connexin30.2 was isolated together with connexin40, connexin43, o ...[more]