Ontology highlight
ABSTRACT:
SUBMITTER: Gefen O
PROVIDER: S-EPMC2329697 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Gefen Orit O Gabay Chana C Mumcuoglu Michael M Engel Giora G Balaban Nathalie Q NQ
Proceedings of the National Academy of Sciences of the United States of America 20080421 16
Phenotypic variability in populations of cells has been linked to evolutionary robustness to stressful conditions. A remarkable example of the importance of cell-to-cell variability is found in bacterial persistence, where subpopulations of dormant bacteria, termed persisters, were shown to be responsible for the persistence of the population to antibiotic treatments. Here, we use microfluidic devices to monitor the induction of fluorescent proteins under synthetic promoters and characterize the ...[more]