Ontology highlight
ABSTRACT:
SUBMITTER: Liu P
PROVIDER: S-EPMC2344103 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Liu P P Ewis H E HE Huang Y J YJ Lu C D CD Tai P C PC Weber I T IT
Acta crystallographica. Section F, Structural biology and crystallization communications 20071121 Pt 12
The sodA gene of Bacillus subtilis was expressed in Escherichia coli, purified and crystallized. The crystal structure of MnSOD was solved by molecular replacement with four dimers per asymmetric unit and refined to an R factor of 21.1% at 1.8 A resolution. The dimer structure is very similar to that of the related enzyme from B. anthracis. Larger structural differences were observed with the human MnSOD, which has one less helix in the helical domain and a longer loop between two beta-strands a ...[more]