Ontology highlight
ABSTRACT:
SUBMITTER: Scott BT
PROVIDER: S-EPMC2349101 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Scott Bruce T BT Olson Nels N Long George L GL Bovill Edwin G EG
Prostaglandins & other lipid mediators 20071109 3-4
Platelet activating factor acetylhydrolase (paf-ah), a potent regulator of platelet activating factor activity, plays an important role in various physiological and pathophysiological functions including development, reproduction, inflammation, hemostasis, and apoptosis. Intracellular paf-ah (paf-ah-Ib) is composed of a regulatory subunit, Pafah1b1, and two highly conserved but non-identical catalytic subunits, Pafah1b2 and Pafah1b3. The present study identifies new splice variants of the Pafah1 ...[more]