Ontology highlight
ABSTRACT:
SUBMITTER: Wu H
PROVIDER: S-EPMC2364725 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Wu H H Romieu I I Sienra-Monge J-J JJ del Rio-Navarro B E BE Burdett L L Yuenger J J Li H H Chanock S J SJ London S J SJ
Genes and immunity 20080313 3
G-protein-coupled receptor for asthma susceptibility (GPRA or GPR154) was identified as an asthma and atopy candidate gene by positional cloning. Some subsequent studies suggest associations of GPRA single nucleotide polymorphisms (SNPs) and haplotypes with asthma or atopy susceptibility. However, the associated SNPs or haplotypes vary among studies. The role of GPRA genetic variation in asthma and atopy remains unsolved. Published data on GRPA variants and asthma come exclusively from Caucasian ...[more]