Ontology highlight
ABSTRACT:
SUBMITTER: Song L
PROVIDER: S-EPMC2367372 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Song Li L Zhao De-gang DG Wu Yong-jun YJ Li Yi Y
Journal of Zhejiang University. Science. B 20080501 5
We investigated the possibility of producing chicken alpha interferon (ChIFN-alpha) in transgenic plants. The cDNA encoding ChIFN-alpha was introduced into lettuce (Lactuca sativa L.) plants by using an agro-infiltration transient expression system. The ChIFN-alpha gene was correctly transcribed and translated in the lettuce plants according to RT-PCR and ELISA assays. Recombinant protein exhibited antiviral activity in vitro by inhibition of vesicular stomatitis virus (VSV) replication on chick ...[more]