Ontology highlight
ABSTRACT:
SUBMITTER: Xing C
PROVIDER: S-EPMC2367604 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
BMC proceedings 20071218
The COMT and DBH genes are physically located at chromosomes 22q11 and 9q34, respectively, and both COMT and DBH are involved in catecholamine metabolism and are strong candidates for certain psychiatric and neurological disorders. Although the genetic determinants for both enzymes' activities have been widely studied, their genetic involvement on gene mRNA expression levels remains unclear. In this study we performed quantitative linkage analysis of COMT and DBH cDNA expression levels, identify ...[more]