Ontology highlight
ABSTRACT:
SUBMITTER: Qayyum A
PROVIDER: S-EPMC4759319 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Qayyum Arqam A Zai Clement C CC Hirata Yuko Y Tiwari Arun K AK Cheema Sheraz S Nowrouzi Behdin B Beitchman Joseph H JH Kennedy James L JL
Current neuropharmacology 20150101 6
Aggressive behaviors have become a major public health problem, and early-onset aggression can lead to outcomes such as substance abuse, antisocial personality disorder among other issues. In recent years, there has been an increase in research in the molecular and genetic underpinnings of aggressive behavior, and one of the candidate genes codes for the catechol-O-methyltransferase (COMT). COMT is involved in catabolizing catecholamines such as dopamine. These neurotransmitters appear to be inv ...[more]