Ontology highlight
ABSTRACT:
SUBMITTER: Hiraoka A
PROVIDER: S-EPMC23864 | biostudies-literature | 1997 Jul
REPOSITORIES: biostudies-literature
Hiraoka A A Sugimura A A Seki T T Nagasawa T T Ohta N N Shimonishi M M Hagiya M M Shimizu S S
Proceedings of the National Academy of Sciences of the United States of America 19970701 14
Multiple growth factors synergistically stimulate proliferation of primitive hematopoietic progenitor cells. A human myeloid cell line, KPB-M15, constitutively produces a novel hematopoietic cytokine, termed stem cell growth factor (SCGF), possessing species-specific proliferative activities. Here we report the molecular cloning, expression, and characterization of a cDNA encoding human SCGF using a newly developed lambdaSHDM vector that is more efficient for differential and expression cloning. ...[more]