Ontology highlight
ABSTRACT:
SUBMITTER: LoGiudice L
PROVIDER: S-EPMC2387080 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
LoGiudice Lisamarie L Sterling Peter P Matthews Gary G
The Journal of neuroscience : the official journal of the Society for Neuroscience 20080301 12
Ribbon synapses release neurotransmitter continuously at high rates, and the ribbons tether a large pool of synaptic vesicles. To determine whether the tethered vesicles are actually released, we tracked vesicles labeled with styryl dye in mouse retinal bipolar cell terminals whose ribbons had been labeled with a fluorescent peptide. We photobleached vesicles in regions with ribbons and without them and then followed recovery of fluorescence as bleached regions were repopulated by labeled vesicl ...[more]