Ontology highlight
ABSTRACT:
SUBMITTER: Graydon CW
PROVIDER: S-EPMC5547071 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Scientific reports 20170807 1
Ribbons are presynaptic structures that mediate synaptic vesicle release in some sensory cells of the auditory and visual systems. Although composed predominately of the protein Ribeye, very little is known about the structural dynamics of ribbons. Here we describe the in vivo mobility and turnover of Ribeye at hair cell ribbon synapses by monitoring fluorescence recovery after photobleaching (FRAP) in transgenic zebrafish with GFP-tagged Ribeye. We show that Ribeye can exchange between halves o ...[more]