Junction-forming aquaporins.
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ABSTRACT:
SUBMITTER: Engel A
PROVIDER: S-EPMC2396442 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Publications
Junction-forming aquaporins.
Engel Andreas A Fujiyoshi Yoshinori Y Gonen Tamir T Walz Thomas T
Current opinion in structural biology 20080114 2
Aquaporins (AQPs) are a family of ubiquitous membrane channels that conduct water and solutes across membranes. This review focuses on AQP0 and AQP4, which in addition to forming water channels also appear to play a role in cell adhesion. We discuss the recently determined structures of the membrane junctions mediated by these two AQPs, the mechanisms that regulate junction formation, and evidence that supports a role for AQP0 and AQP4 in cell adhesion. ...[more]
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