Ontology highlight
ABSTRACT:
SUBMITTER: Maurer JA
PROVIDER: S-EPMC2397327 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Biophysical journal 20080307 12
The structure of the C-terminal domain of the mechanosensitive channel of large conductance (MscL) has generated significant controversy. As a result, several structures have been proposed for this region: the original crystal structure (1MSL) of the Mycobacterium tuberculosis homolog (Tb), a model of the Escherichia coli homolog, and, most recently, a revised crystal structure of Tb-MscL (2OAR). To understand which of these structures represents a physiological conformation, we measured the imp ...[more]