Ontology highlight
ABSTRACT:
SUBMITTER: Vetting MW
PROVIDER: S-EPMC2414306 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Vetting Matthew W MW Frantom Patrick A PA Blanchard John S JS
The Journal of biological chemistry 20080404 23
The glycosyltransferase termed MshA catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to 1-L-myo-inositol-1-phosphate in the first committed step of mycothiol biosynthesis. The structure of MshA from Corynebacterium glutamicum was determined both in the absence of substrates and in a complex with UDP and 1-L-myo-inositol-1-phosphate. MshA belongs to the GT-B structural family whose members have a two-domain structure with both domains exhibiting a Rossman-type fold. Bind ...[more]