Ontology highlight
ABSTRACT:
SUBMITTER: Manson SC
PROVIDER: S-EPMC2414440 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Manson S C SC Wegner C C Filippi M M Barkhof F F Beckmann C C Ciccarelli O O De Stefano N N Enzinger Christian C Fazekas F F Agosta F F Gass A A Hirsch J J Johansen-Berg H H Kappos L L Korteweg T T Polman C C Mancini L L Manfredonia F F Marino S S Miller D H DH Montalban X X Palace J J Rocca M M Ropele S S Rovira A A Smith S S Thompson A A Thornton J J Yousry T T Frank J A JA Matthews P M PM
Experimental brain research 20080131 1
Motor control demands coordinated excitation and inhibition across distributed brain neuronal networks. Recent work has suggested that multiple sclerosis (MS) may be associated with impairments of neuronal inhibition as part of more general progressive impairments of connectivity. Here, we report results from a prospective, multi-centre fMRI study designed to characterise the changes in patients relative to healthy controls during a simple cued hand movement task. This study was conducted at eig ...[more]