Analysis of genomic admixture in Uyghur and its implication in mapping strategy.
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ABSTRACT:
SUBMITTER: Xu S
PROVIDER: S-EPMC2427216 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Publications
Analysis of genomic admixture in Uyghur and its implication in mapping strategy.
Xu Shuhua S Huang Wei W Qian Ji J Jin Li L
American journal of human genetics 20080320 4
The Uyghur (UIG) population, settled in Xinjiang, China, is a population presenting a typical admixture of Eastern and Western anthropometric traits. We dissected its genomic structure at population level, individual level, and chromosome level by using 20,177 SNPs spanning nearly the entire chromosome 21. Our results showed that UIG was formed by two-way admixture, with 60% European ancestry and 40% East Asian ancestry. Overall linkage disequilibrium (LD) in UIG was similar to that in its paren ...[more]
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