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Analysis of genetic admixture in Uyghur using the 26 Y-STR loci system.


ABSTRACT: The Uyghur population has experienced extensive interaction with European and Eastern Asian populations historically. A set of high-resolution genetic markers could be useful to infer the genetic relationships between the Uyghur population and European and Asian populations. In this study we typed 100 unrelated Uyghur males living in southern Xinjiang at 26 Y-STR loci. Using the high-resolution 26 Y-STR loci system, we investigated genetic and phylogenetic relationship between the Uyghur population and 23 reference European or Asian populations. We found that the Uyghur population exhibited a genetic admixture of Eastern Asian and European populations, and had a slightly closer relationship with the selected European populations than the Eastern Asian populations. We also demonstrated that the 26 Y-STR loci system was potentially useful in forensic sciences because it has a large power of discrimination and rarely exhibits common haplotypes. However, ancestry inference of Uyghur samples could be challenging due to the admixed nature of the population.

SUBMITTER: Bian Y 

PROVIDER: S-EPMC4740765 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Analysis of genetic admixture in Uyghur using the 26 Y-STR loci system.

Bian Yingnan Y   Zhang Suhua S   Zhou Wei W   Zhao Qi Q   Siqintuya   Zhu Ruxin R   Wang Zheng Z   Gao Yuzhen Y   Hong Jie J   Lu Daru D   Li Chengtao C  

Scientific reports 20160204


The Uyghur population has experienced extensive interaction with European and Eastern Asian populations historically. A set of high-resolution genetic markers could be useful to infer the genetic relationships between the Uyghur population and European and Asian populations. In this study we typed 100 unrelated Uyghur males living in southern Xinjiang at 26 Y-STR loci. Using the high-resolution 26 Y-STR loci system, we investigated genetic and phylogenetic relationship between the Uyghur populat  ...[more]

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