Ontology highlight
ABSTRACT:
SUBMITTER: Hamblin K
PROVIDER: S-EPMC2440562 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Hamblin Karleigh K Standley Daron M DM Rogers Matthew B MB Stechmann Alexandra A Roger Andrew J AJ Maytum Robin R van der Giezen Mark M
Molecular microbiology 20080429 6
The anaerobic lifestyle of the intestinal parasite Blastocystis raises questions about the biochemistry and function of its mitochondria-like organelles. We have characterized the Blastocystis succinyl-CoA synthetase (SCS), a tricarboxylic acid cycle enzyme that conserves energy by substrate-level phosphorylation. We show that SCS localizes to the enigmatic Blastocystis organelles, indicating that these organelles might play a similar role in energy metabolism as classic mitochondria. Although a ...[more]