Ontology highlight
ABSTRACT:
SUBMITTER: Liu Z
PROVIDER: S-EPMC2446680 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Liu Zhongmei Z Takazaki Hiroko H Nakazawa Yuki Y Sakato Miho M Yagi Toshiki T Yasunaga Takuo T King Stephen M SM Kamiya Ritsu R
Eukaryotic cell 20080516 7
The outer dynein arm of Chlamydomonas flagella contains three heavy chains (alpha, beta, and gamma), each of which exhibits motor activity. How they assemble and cooperate is of considerable interest. Here we report the isolation of a novel mutant, oda2-t, whose gamma heavy chain is truncated at about 30% of the sequence. While the previously isolated gamma chain mutant oda2 lacks the entire outer arm, oda2-t retains outer arms that contain alpha and beta heavy chains, suggesting that the N-term ...[more]