Ontology highlight
ABSTRACT:
SUBMITTER: Daniels CC
PROVIDER: S-EPMC2453751 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Daniels Candelaria C CC Rovnak Joel J Quackenbush Sandra L SL
Virology 20080317 2
Walleye dermal sarcoma virus is a complex retrovirus that is associated with walleye dermal sarcomas that are seasonal in nature. Fall developing tumors contain low levels of spliced accessory gene transcripts A and B, suggesting a role for the encoded proteins, Orf A and Orf B, in oncogenesis. In explanted tumor cells the 35 kDa Orf B accessory protein is localized to the cell periphery in structures similar to focal adhesions and along actin stress fibers. Similar localization was observed in ...[more]