Unknown

Dataset Information

0

Homologous recombination is unlikely to play a major role in influenza B virus evolution.


ABSTRACT: Influenza B viruses cause a significant amount of morbidity and mortality. The occurrence of homologous recombination in influenza viruses is controversial. To determine the extent of homologous recombination in influenza B viruses, recombination analyses of 2,650 sequences representing all eight segments of the influenza B viruses were carried out. Only four sequences were indentified as putative recombinants, which were verified using phylogenetic methods. However, the mosaics detected here were much likely to represent cases of laboratory-generated artificial recombinants. As in other myxoviruses, it is unlikely that homologous recombination plays a major role in influenza B virus evolution.

SUBMITTER: Han GZ 

PROVIDER: S-EPMC2474605 | biostudies-literature | 2008

REPOSITORIES: biostudies-literature

altmetric image

Publications

Homologous recombination is unlikely to play a major role in influenza B virus evolution.

Han Guan-Zhu GZ   Liu Xi-Ping XP   Li Si-Shen SS  

Virology journal 20080527


Influenza B viruses cause a significant amount of morbidity and mortality. The occurrence of homologous recombination in influenza viruses is controversial. To determine the extent of homologous recombination in influenza B viruses, recombination analyses of 2,650 sequences representing all eight segments of the influenza B viruses were carried out. Only four sequences were indentified as putative recombinants, which were verified using phylogenetic methods. However, the mosaics detected here we  ...[more]

Similar Datasets

| S-EPMC2862710 | biostudies-literature
| S-EPMC7127770 | biostudies-literature
| S-EPMC4650164 | biostudies-literature
| S-EPMC4315363 | biostudies-literature
| S-EPMC2346757 | biostudies-literature
| S-EPMC5386261 | biostudies-literature
| S-EPMC4666801 | biostudies-literature
| S-EPMC3505186 | biostudies-literature
| S-EPMC4150228 | biostudies-literature
| S-EPMC7360064 | biostudies-literature