Assignment of isochores for all completely sequenced vertebrate genomes using a consensus.
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ABSTRACT:
SUBMITTER: Schmidt T
PROVIDER: S-EPMC2481423 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Publications
Assignment of isochores for all completely sequenced vertebrate genomes using a consensus.
Schmidt Thorsten T Frishman Dmitrij D
Genome biology 20080630 6
We show that although the currently available isochore mapping methods agree on the isochore classification of about two-thirds of the human DNA, they produce significantly different results with regard to the location of isochore boundaries and isochore length distribution. We present a new consensus isochore assignment method based on majority voting and provide IsoBase, a comprehensive on-line database of isochore maps for all completely sequenced vertebrate genomes. ...[more]
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