Ontology highlight
ABSTRACT:
SUBMITTER: Trinh CH
PROVIDER: S-EPMC2483477 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Trinh Chi-Hung CH Liu Yang Y Phillips Simon E V SE Phillips-Jones Mary K MK
Acta crystallographica. Section D, Biological crystallography 20070116 Pt 2
The response regulator VicR from the Gram-positive bacterium Enterococcus faecalis forms part of the two-component signal transduction system of the YycFG subfamily. The structure of the DNA-binding domain of VicR, VicR(c), has been solved and belongs to the winged helix-turn-helix family. It is very similar to the DNA-binding domains of Escherichia coli PhoB and OmpR, despite low sequence similarity, but differs in two important loops. The alpha-loop, which links the two helices of the helix-tu ...[more]