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Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore.

ABSTRACT: In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100 fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).

SUBMITTER: Du L

PROVIDER: S-EPMC2490821 | biostudies-literature | 2008 May

REPOSITORIES: biostudies-literature

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Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore.

Du Lupei L Li Minyong M Zheng Shilong S Wang Binghe B

Tetrahedron letters 20080501 19

In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100 fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS). ...[more]

PMID: 19081820

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