Ontology highlight
ABSTRACT:
SUBMITTER: Hussain SK
PROVIDER: S-EPMC2497438 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Hussain Shehnaz K SK Madeleine Margaret M MM Johnson Lisa G LG Du Qin Q Malkki Mari M Wilkerson Hui-Wen HW Farin Federico M FM Carter Joseph J JJ Galloway Denise A DA Daling Janet R JR Petersdorf Effie W EW Schwartz Stephen M SM
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080701 7
Cigarette smoking is an established cofactor to human papillomavirus (HPV) in the development of cervical and vulvar squamous cell carcinoma (SCC), and may influence risk through an immunosuppressive pathway. Genetic variation in interleukin 2 (IL2), associated in some studies with the inhibition of HPV-targeted immunity, may modify the effect of smoking on the risk of HPV-related anogenital cancers. We conducted a population-based case-only study to measure the departure from a multiplicative j ...[more]