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Concise, enantioselective total synthesis of (-)-alstonerine.


ABSTRACT: A novel enantioselective total synthesis of (-)-alstonerine has been completed that requires only 15 steps from L-tryptophan. The synthesis features the first application of a Pauson-Khand reaction to synthesize an azabridged bicyclic skeleton. [reaction: see text]

SUBMITTER: Miller KA 

PROVIDER: S-EPMC2516964 | biostudies-literature | 2007 Mar

REPOSITORIES: biostudies-literature

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Concise, enantioselective total synthesis of (-)-alstonerine.

Miller Kenneth A KA   Martin Stephen F SF  

Organic letters 20070214 6


A novel enantioselective total synthesis of (-)-alstonerine has been completed that requires only 15 steps from L-tryptophan. The synthesis features the first application of a Pauson-Khand reaction to synthesize an azabridged bicyclic skeleton. [reaction: see text] ...[more]

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