Ontology highlight
ABSTRACT:
SUBMITTER: Goetz AE
PROVIDER: S-EPMC3985696 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Goetz Adam E AE Silberstein Amanda L AL Corsello Michael A MA Garg Neil K NK
Journal of the American Chemical Society 20140218 8
We report the enantiospecific total synthesis of (+)-tubingensin A. Our synthesis features an aryne cyclization to efficiently introduce the vicinal quaternary stereocenters of the natural product and proceeds in only nine steps (longest linear sequence) from known compounds. ...[more]