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Catalytic enantioselective O-H insertion reactions.

ABSTRACT: The first effective method for catalytic enantioselective insertions into O-H bonds has been developed. Specifically, a copper/bisazaferrocene catalyst couples alcohols such as 2-trimethylsilylethanol with alpha-aryl-alpha-diazo esters in high yield and good ee.

SUBMITTER: Maier TC

PROVIDER: S-EPMC2517123 | biostudies-literature | 2006 Apr

REPOSITORIES: biostudies-literature

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Catalytic enantioselective O-H insertion reactions.

Maier Thomas C TC Fu Gregory C GC

Journal of the American Chemical Society 20060401 14

The first effective method for catalytic enantioselective insertions into O-H bonds has been developed. Specifically, a copper/bisazaferrocene catalyst couples alcohols such as 2-trimethylsilylethanol with alpha-aryl-alpha-diazo esters in high yield and good ee. ...[more]

PMID: 16594695

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