Ontology highlight
ABSTRACT:
SUBMITTER: Muthiah C
PROVIDER: S-EPMC2525510 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20070622 15
Two distinct approaches have been developed for the synthesis of chlorins bearing formyl groups: (1) reaction of an acetal-substituted 1-acyldipyrromethane with 2,3,5,6-tetrahydro-1,3,3-trimethyldipyrrin to give upon hydrolysis a 5-formylchlorin and (2) Pd-mediated coupling of a bromochlorin with a one-carbon synthon (hydroxymethyl tributyltin or CO) to give a 13-, 15-, or 3,13-formylchlorin. The zinc chlorins exhibit long-wavelength peak absorption maxima ranging from 626 to 667 nm, indicating ...[more]