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Enantioselective total synthesis of (+)-gliocladin C.

ABSTRACT: The first total synthesis of gliocladin C, a fungal-derived marine alkaloid containing a rare trioxopiperazine fragment, is reported. This asymmetric synthesis establishes the absolute configuration of this structurally novel natural product. [reaction: see text].

SUBMITTER: Overman LE

PROVIDER: S-EPMC2526118 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature

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Enantioselective total synthesis of (+)-gliocladin C.

Overman Larry E LE Shin Youseung Y

Organic letters 20070101 2

The first total synthesis of gliocladin C, a fungal-derived marine alkaloid containing a rare trioxopiperazine fragment, is reported. This asymmetric synthesis establishes the absolute configuration of this structurally novel natural product. [reaction: see text]. ...[more]

PMID: 17217299

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