The importance of dynamics in substrate-assisted catalysis and specificity.
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ABSTRACT:
SUBMITTER: Xu Q
PROVIDER: S-EPMC2530918 | biostudies-literature | 2006 May
REPOSITORIES: biostudies-literature
Publications
The importance of dynamics in substrate-assisted catalysis and specificity.
Xu Qin Q Guo Haobo H Wlodawer Alexander A Guo Hong H
Journal of the American Chemical Society 20060501 18
The QM/MM MD and free energy simulations show that the dynamics involving a His residue at the P1 site of the substrate may play an important role in substrate-assisted catalysis and specificity for a serine-carboxyl peptidase. ...[more]
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