Ontology highlight
ABSTRACT:
SUBMITTER: Charles PC
PROVIDER: S-EPMC2531187 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Charles Peter C PC Alder Brian D BD Hilliard Eleanor G EG Schisler Jonathan C JC Lineberger Robert E RE Parker Joel S JS Mapara Sabeen S Wu Samuel S SS Portbury Andrea A Patterson Cam C Stouffer George A GA
BMC medical genomics 20080818
<h4>Background</h4>Strong epidemiologic evidence correlates tobacco use with a variety of serious adverse health effects, but the biological mechanisms that produce these effects remain elusive.<h4>Results</h4>We analyzed gene transcription data to identify expression spectra related to tobacco use in circulating leukocytes of 67 Caucasian male subjects. Levels of cotinine, a nicotine metabolite, were used as a surrogate marker for tobacco exposure. Significance Analysis of Microarray and Gene S ...[more]