Ontology highlight
ABSTRACT:
SUBMITTER: Hou Y
PROVIDER: S-EPMC2533136 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Hou Yanpeng Y Cao Shugeng S Brodie Peggy P Miller James S JS Birkinshaw Chris C Ratovoson Fidisoa F Rakotondrajaona Roland R Andriantsiferana Rabodo R Rasamison Vincent E VE Kingston David G I DG
Journal of natural products 20071229 1
Bioassay-guided fractionation of an ethanol extract of a Madagascar collection of the fruits of Cordyla madagascariensis ssp. madagascariensis led to the isolation of the four new cassane diterpenoids 1-4. The 1H and 13C NMR spectra of all compounds were fully assigned using a combination of 2D NMR experiments, including COSY, HSQC, HMBC, and ROESY sequences. All of the isolates were tested against the A2780 human ovarian cancer cell line, and compounds 1 and 2 showed mild antiproliferative acti ...[more]