Ontology highlight
ABSTRACT:
SUBMITTER: Hou Y
PROVIDER: S-EPMC2847016 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Hou Yanpeng Y Cao Shugeng S Brodie Peggy J PJ Miller James S JS Birkinshaw Chris C Andrianjafy Mamisoa N MN Andriantsiferana Rabodo R Rasamison Vincent E VE TenDyke Karen K Shen Yongchun Y Suh Edward M EM Kingston David G I DG
Phytochemistry 20100113 5-6
Fractionation of an ethanol extract of a Madagascar collection of the leaves and fruit of Cassipourea lanceolata Tul. led to the isolation of three euphane triterpenoids 1-3. The (1)H and (13)C NMR spectra of all compounds were fully assigned using a combination of 2D NMR experiments, including COSY, TOCSY, HSQC (HMQC), HMBC and ROESY sequences. The three compounds showed weak antiproliferative activities against the A2780 human ovarian cancer cell line, with IC(50) values of 25, 25 and 32 micro ...[more]